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Cake day: December 15th, 2024

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  • Blocking sEH increased epoxy-oxylipin levels, helped pain resolve more quickly, and sharply reduced the number of intermediate monocytes found in both the blood and tissue. These immune cells have been linked to persistent inflammation and the progression of inflammatory disease.

    redness/swelling aren’t the only markers of inflammation in this context, as the cells that kick off the response do more harm than good when they wear out their welcome.

    monocytes are white blood cells that develop in bone marrow. i’m curious/interested in whether the same treatment affects mast cells that develop in connective tissue